There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

Nuclear pore complexes (NPCs) govern macromolecular transport between the nucleus and cytoplasm and serve as key positional markers within the nucleus. Several protein components of yeast NPCs have ...

In diagrams and illustrations of cells, DNA is sometimes shown as a mass in the cell's nucleus, like a bowl of ramen noodles. For many years, it's been standard practice to take images of cells that ...

Using computer simulations, chemists have discovered how nuclear bodies called nucleoli interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus about one-tenth as wide as a human hair while making sure the all-important ...

Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome. Chromatin is a complex of DNA and protein found in eukaryotic cells; regions of ...

The Dere lab specializes in kidney cancer and VHL (von Hippel Lindau) disease focused on understand fundamental aspects of how non-chromatin functions of chromatin modifiers contribute to oncogenesis.

Professor Corey Neu and PhD graduate Benjamin Seelbinder. Header image: Tissues with diverse structural and mechanical characteristics. Biomedical Engineering Professor Corey Neu and Benjamin ...